Summary

 

  • As per the Therapeutic Interchange Policy, medication orders for ceftriaxone 2 grams IV q24h were previously interchanged to 1 gram IV q24h for most indications*. 
  • Determining the appropriateness of an order for ceftriaxone 2 grams from the pharmacy dispensary is challenging. 
  • In addition, certain populations (e.g., obesity, critical illness) may be at higher risk of treatment failure with 1 gram dosing.

 

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