Summary
- As per the Therapeutic Interchange Policy, medication orders for ceftriaxone 2 grams IV q24h were previously interchanged to 1 gram IV q24h for most indications*.
- Determining the appropriateness of an order for ceftriaxone 2 grams from the pharmacy dispensary is challenging.
- In addition, certain populations (e.g., obesity, critical illness) may be at higher risk of treatment failure with 1 gram dosing.