Summary

  • Fluoroquinolones are NOT first line treatments for most infections, including sinusitis, urinary tract infections, skin infections, pharyngitis, acute exacerbations of chronic obstructive pulmonary disease , and outpatient-treated community-acquired pneumonia.
  • Health Canada and the U.S. Food and Drug Administration have released warnings of serious adverse effects affecting tendons, the cardiovascular system, and the central and peripheral nervous systems.
  • Use an alternative treatment in patients at high risk of developing fluoroquinolone adverse events.

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