Fluoroquinolones are NOT first line treatments for most infections, including sinusitis, urinary tract infections, skin infections, pharyngitis, acute exacerbations of chronic obstructive pulmonary disease , and outpatient-treated community-acquired pneumonia.
Health Canada and the U.S. Food and Drug Administration have released warnings of serious adverse effects affecting tendons, the cardiovascular system, and the central and peripheral nervous systems.
Use an alternative treatment in patients at high risk of developing fluoroquinolone adverse events.
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