UPDATED: July 28, 2025. Original Post: November 8, 2017

Developing a clear question is an important first step when researching information to guide your work and/or decision-making, and when preparing for a potential research project. In health care, practitioners and researchers are faced with complex questions which make starting the research process a daunting task. A well-built question is clear, focused, and summarizes the issue to be investigated. Determining the type of question will help you select the best resource to consult for your answer.
Background vs. Foreground Questions
Background questions are used to gather general information, typically asking the 5Ws: Who? What? When? Where? Why? To answer these questions, start with general resources, such as overview textbooks, summaries, medical directories, etc.
Example: Looking for general information on diabetes care? Search for resources using Library Services' Discover search. Use the filters on the left-hand side of the page to retrieve results for books to find general information on the disease and its presentation.
Other helpful resources for answering background questions include Library Services’ Subject Guides, which contain best bets on library resources for specific topics in healthcare research. Need resources that inform patient care? Our collection of Clinical Practice Supports highlights information and tools for clinical staff.
Building Foreground Questions
Foreground questions are specific and complex. They often consider multiple factors to guide decision making and/or inform further research.
Example: In women with migraine and aura, how does use of combination birth control pills affect risk of stroke compared to progestin-only birth control?
Clearly articulating a foreground question and identifying key components can be challenging. Using the PICO(T) model can help you identify your key concepts and build your question before examining the literature.
PICO Example:
| Patient or Problem: | Women with migraine or aura |
| Intervention: | Progestin-only birth control pills |
| Comparison: | Combination birth control pills |
| Outcome: | Risk of Stroke |
| Time Period: | Optional |
This Evidence Based Practice module from Dalhousie University's Kellogg Library takes you through the steps of creating an answerable clinical question using PICO.
Structuring your Search
Using PICO to develop your question will help you identify key search concepts. Tools like a search planning grid can help you plan and organize your PICO criteria into search terms. Once identified, additional terms can be derived from synonyms and related concepts to expand your search results.
Once you have determined the key terms for your search, you will be able to search databases and search engines by combining your terms using Boolean operators (AND, OR, NOT).
Still have Questions?
Visit Library Services’ Searching guide for more tips and assistance. Book a one-on-one consultation with a Librarian Educator to discuss building effective research questions or request a custom education session on the topic. Want to get started on searching? Try out your question-building skills by submitting a literature search request. We bet your results will be more relevant!
Happy searching!

Selena MacDonald
Librarian Educator
Nova Scotia Hospital, Central Zone












in the top right.
at the top of the full text.
let you navigate between all the results from the search results page.





Check for full text: We may not currently have access to the article. In that case, request a copy using the Document Delivery form attached to the article’s library record. Click the article’s title or Check for full text (3), then scroll down to complete the form.
UPDATED: November 17, 2025. Original Post: July 20, 2020
Integrating the best available health evidence into decision-making processes is an important part of evidence-based practice. However, before applying clinical research findings to patient care, health care providers must determine whether the research findings are valid.
It is important to remember that published studies are not necessarily trustworthy. Healthcare research must be evaluated before being used to guide clinical decisions. Critical appraisal provides a framework for this evaluation.
What is critical appraisal?
Critical appraisal is “the process of carefully and systematically examining research to judge its trustworthiness, and its value and relevance in a particular context.” (CASP)
To critically appraise clinical research is to look at its methodological quality, trustworthiness, and applicability to a patient’s specific situation. Critical appraisal helps us ask two essential questions about a particular research study (Sala Serra & Domingo Torrell, 2022):
When should critical appraisal be conducted?
Research should always be critically appraised, no matter its intended use. Such uses may include:
For example, if a recently published study in your discipline suggests a therapy is effective and safe for patients, critically appraising the study ensures the findings are valid and unbiased, and the therapy is appropriate for the specific needs of your patient.
Beyond clinical scenarios, critical appraisal is also a key part of evidence synthesis. As part of the systematic review process, for example, articles included in the review are critically appraised for validity. This ensures that the integrity of the overall review is not impacted by the quality of the individual studies included.
Using critical appraisal checklists
Any type of clinical study can be critically appraised, and each study type has its own checklist. Critical appraisal checklists provide a step-by-step guide through the appraisal process. There are many critical appraisal tools available from organizations that are experts in evidence-based research evaluation, including:
For example, CASP’s Randomised Controlled Trial Checklist includes questions about study methodology such as:
Critical appraisal for antiracism is rarely addressed in standard tools. To avoid overlooking underrepresented patient populations, consider supplementing your chosen tool with Naicker’s Critically Appraising for Antiracism Tool.
Critical appraisal can be conducted without the use of a formal checklist, but using an established set of appraisal criteria may be helpful if you want to ensure that you are consistent in how you appraise clinical research.
For more info on critical appraisal in your daily work or a larger project, email AskLibrary@nshealth.ca or book a one-on-one consultation with a librarian.
Additional Support
In-depth Resources in Library Services' Searching subject guide.
References
1. CASP - Critical Appraisal Skills Programme. (2025, October 15). What is critical appraisal?. https://casp-uk.net/what-is-critical-appraisal/
2. Naicker, R. (2022). Critically appraising for antiracism. Education for Information, 38(4), 291–308. https://doi.org/10.3233/EFI-220052
3. Sala Serra, M., & Domingo Torrell, L. (2022). Validity of a study: Internal and external validity. Cirugia espanola, 100(10), 649–651. https://doi.org/10.1016/j.cireng.2021.12.007
Selena MacDonald
Librarian Educator
Nova Scotia Hospital, Central Zone